A one-day scientific meeting presenting integrated structural biology research activities within the Instruct-ERIC community. The event is free and open to everyone, but registration is required.
Data: 20 OTTOBRE 2026 dalle 10:45 alle 17:50
Luogo: CERM-UNIFI Via L. Sacconi 6, Sesto Fiorentino
Registration is required.
AGENDA
10:45-10:50 Lucia Banci (University of Florence)
Welcome
10:50-11:10 Beatrice Vallone (University of Rome 'La Sapienza')
Structural dynamics of HER3 paves the way to mechanism based drug design
11:15-11:35 Winfried Weissenhorn (Institut de Biologie Structurale)
Cleaving membrane necks with ESCRT-III and VPS4
11:40-12:00 Harald Schwalbe (Goethe University Frankfurt; Instruct-ERIC Director)
4D structural biology: using light as trigger to understand protein, RNA, and DNA
refolding
12:05-12:15 Roberta Pierattelli (University of Florence)
Introduction to CERM/CIRMMP, Instruct-IT
12:15-13:45 Laboratory Visit & Lunch
13:45-14:05 Barbara Zambelli (University of Bologna)
The disordered tail of NDRG1 in lung cancer: from molecular interactions to small
molecules
14:10-14:30 Jiri Novaceck (CEITEC Masaryk University)
Plum Pox Virus structure and stabilization of virus-like particles
14:35-14:55 Alessandro Piai (IRBM SpA)
A Ligand-Observed NMR Strategy for Hit Discovery and Qualification: the SARSCoV-
2 NSP13 Case Study
15:00-15:20 Michael Assfalg (University of Verona)
Structural insights into tau ubiquitination
15:25-15:45 Enrico Luchinat (University of Florence)
NMR in living human cells: applications to protein conformation and ligand
binding
15:50-16:05 Coffee Break
16:05-16:25 Linda Cerofolini (University of Florence)
NMR for the characterization of challenging biotherapeutics: antibodies,
enzymes, and metallo-enzymes
16:30-16:50 Marco Schiavina (University of Florence)
Broadening the NMR view by narrowing the linewidth: exploring Intrinsically
Disordered Proteins and their interactions
16:55-17:15 Matteo Tassinari (Human Technopole)
Molecular Mechanism of Thyroid Hormone Transport by MCT8 and MCT10
17:20-17:40 Antonio Rosato (University of Florence)
Applications of machine learning and molecular dynamics simulations to the
investigation of metalloproteins
17:45-17:50 Lucia Banci (University of Florence)
Closure Remarks